ACE inhibitors after myocardial infarction.

What to expect from ACE inhibitors after myocardial infarction.

ACE inhibitors in acute myocardial infarction: patient selection and timing.

Angiotensin-converting enzyme inhibitors have earned their place along with aspirin, b-blockers, and thrombolytic agents as medical therapies proven to reduce mortality rates in acute myocardial infarction. The results of well-conducted, randomized, controlled clinical trials have been so consistent and so conclusive that the emphasis now shifts from research to implementation. Because the tria...

ACE inhibitors after myocardial infarction: patient selection or treatment for all?

It is now clear that angiotensin-converting enzyme (ACE) inhibitors have an important role in the management of patients after myocardial infarction. Several clinical trials have shown statistically significant reductions in mortality (SAVE, AIRE, GISSI-3, ISIS4).1-4 Some may argue that the weight of evidence favours wide, if not universal, use of ACE inhibitors among post-infarct patients. Doe...

The comparative treatment effectiveness and safety of tissue versus non-tissue ace inhibitors among the elderly after acute myocardial infarction

Angiotensin Converting Enzyme (ACE) inhibitors are one of the recommended prevention therapy for patients with acute myocardial infarction (AMI) in the clinical guidelines. Two types (tissue and non-tissue) of ACE inhibitors are available with huge cost difference but the comparative treatment benefit and risk between them are unclear. The objective of this study was to investigate the comparat...

Changes in protease inhibitors after acute myocardial infarction.

Plasma levels of fibrinogen, alpha1-antitrypsin, alpha2-macroglobulin, antithrombin III, and C1 inactivator were measured serially for 10 days in 11 patients after acute myocardial infarction. Both fibrinogen and alpha1-antitrypsin rose markedly to reach peak levels 5-7 days after infarction while C1 inactivator levels rose slowly with the highest observed mean level on the 10th postinfarction ...